CUX2

GENERAL INFORMATION

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Gene name

CUX2

Gene description

Cut-like homeobox 2

Protein class

Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Transcription factors

Predicted localization

Intracellular,Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (cerebral cortex, liver, prostate, thyroid gland)
GTEx:Group enriched (cerebral cortex, liver, prostate, thyroid gland)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic positivity in several different tissue types. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Sub cellular location is contradicted by external data.

Data reliability

Uncertain based on 1 antibody.
HPA044772
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (cerebral cortex, liver, prostate, thyroid gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebral cortex, liver, prostate, thyroid gland)

Organ

Expression



GENE INFORMATION

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Gene name

CUX2 (HGNC Symbol)

Synonyms

CDP2, CUTL2, KIAA0293

Description

Cut-like homeobox 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is located on chromosome on chromosome 7. Two pseudogenes of this gene have been identified on chromosomes 10 and 4. [provided by RefSeq, Jan 2013]

Chromosome

12

Cytoband

Chromosome location (bp)

111034024 - 111350554

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111249 (version 78.38)

Entrez gene

23316

UniProt

O14529 (UniProt - Evidence at protein level)

neXtProt

NX_O14529

Antibodypedia

CUX2 antibodies


PROTEIN BROWSER

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ENST00000261726
 
ENST00000397643
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CUX2-001 ENSP00000261726
ENST00000261726
O14529
Show all »
Show » Show » 1486 161.7 No 0
CUX2-002 ENSP00000380765
ENST00000397643
F5GWR6
Show all »
Show » 251 28.6 No 1