ART4

GENERAL INFORMATION

? »

Gene name

ART4

Gene description

ADP-ribosyltransferase 4 (Dombrock blood group)

Protein class

Blood group antigen proteins
CD markers
Enzymes
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enhanced (liver, spleen)
GTEx:Tissue enhanced (liver, spleen)

Protein evidence

Evidence at protein level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA040879
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enhanced (liver, spleen)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (liver, spleen)

Organ

Expression



GENE INFORMATION

? »

Gene name

ART4 (HGNC Symbol)

Synonyms

CD297, DO, DOK1

Description

ADP-ribosyltransferase 4 (Dombrock blood group) (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that contains a mono-ADP-ribosylation (ART) motif. It is a member of the ADP-ribosyltransferase gene family but enzymatic activity has not been demonstrated experimentally. Antigens of the Dombrock blood group system are located on the gene product, which is glycosylphosphatidylinosotol-anchored to the erythrocyte membrane. Allelic variants, some of which lead to adverse transfusion reactions, are known. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

p12.3

Chromosome location (bp)

14825569 - 14843495

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111339 (version 78.38)

Entrez gene

420

UniProt

Q93070 (UniProt - Evidence at transcript level)

neXtProt

NX_Q93070

Antibodypedia

ART4 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000228936
 
ENST00000420600
 
ENST00000430129
 
ENST00000544616
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ART4-001 ENSP00000228936
ENST00000228936
Q93070
Show all »
Show » Show » 314 35.9 Yes 1
ART4-002 ENSP00000405689
ENST00000420600
H7C2G2
Show all »
Show » Show » 273 31.5 Yes 0
ART4-003 ENSP00000412735
ENST00000430129
Q3KZ30
Show all »
Show » Show » 65 7.1 Yes 0
ART4-004 ENSP00000442877
ENST00000544616
Q3KZ29
Show all »
Show » 41 4.4 Yes 0