SLCO1B3

GENE INFORMATION

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Gene name

SLCO1B3 (HGNC Symbol)

Synonyms

OATP1B3, OATP8, SLC21A8

Description

solute carrier organic anion transporter family, member 1B3 (HGNC Symbol)

Entrez gene summary

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. [provided by RefSeq, Feb 2012]

Chromosome

12 (Chromosome progress)

Cytoband

p12.2

Chromosome location (bp)

20963636 - 21243040

Ensembl

ENSG00000111700 (version 73.37)

Entrez gene

28234

UniProt

Q9NPD5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NPD5

Antibodypedia

SLCO1B3 antibodies
 

PROTEIN VIEW

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SLCO1B3-001
 
SLCO1B3-003
 
SLCO1B3-005
 
SLCO1B3-201
 
SLCO1B3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLCO1B3-001 ENSP00000370956
ENST00000381545
Q9NPD5
Show all »
Show » Show » 702 77.4 No >9
SLCO1B3-003 ENSP00000442000
ENST00000540853
F5H8K0
Show all »
Show » Show » 291 32.2 No 5
SLCO1B3-005 ENSP00000443225
ENST00000544370
H0YGG9
Show all »
Show » Show » 479 52.8 No 7
SLCO1B3-201 ENSP00000261196
ENST00000261196
Q9NPD5
Show all »
Show » Show » 702 77.4 No >9
SLCO1B3-202 ENSP00000451758
ENST00000553473
Q5JAR4
Show all »
Show » Show » 748 82.5 No >9