DSE

GENERAL INFORMATION

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Gene name

DSE

Gene description

Dermatan sulfate epimerase

Protein class

Disease related genes
Enzymes
Potential drug targets
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues exhibited weak to moderate cytoplasmic and/or nuclear positivity. Glial cells and most lymphoid tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA014764
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

DSE (HGNC Symbol)

Synonyms

DSEPI, SART2

Description

Dermatan sulfate epimerase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q22.1

Chromosome location (bp)

116254173 - 116441261

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111817 (version 78.38)

Entrez gene

29940

UniProt

Q9UL01 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UL01

Antibodypedia

DSE antibodies


PROTEIN BROWSER

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ENST00000331677
 
ENST00000359564
 
ENST00000430252
 
ENST00000452085
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DSE-002 ENSP00000332151
ENST00000331677
Q9UL01
Show all »
Show » Show » 958 109.8 Yes 2
DSE-003 ENSP00000404049
ENST00000452085
Q9UL01
Show all »
Show » Show » 958 109.8 Yes 2
DSE-005 ENSP00000397597
ENST00000430252
X6REM1
Show all »
Show » 144 16.5 Yes 0
DSE-201 ENSP00000352567
ENST00000359564
Q9UL01
Show all »
Show » Show » 958 109.8 Yes 2