MAK

GENE INFORMATION

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Gene name

MAK (HGNC Symbol)

Synonyms

dJ417M14.2

Description

male germ cell-associated kinase (HGNC Symbol)

Entrez gene summary

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

Chromosome

6 (Chromosome progress)

Cytoband

p24.2

Chromosome location (bp)

10762956 - 10838764

Ensembl

ENSG00000111837 (version 73.37)

Entrez gene

4117

UniProt

P20794 (UniProt - Evidence at protein level)

neXtProt

NX_P20794

Antibodypedia

MAK antibodies
 

PROTEIN VIEW

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MAK-001
 
MAK-002
 
MAK-201
 
MAK-202
 
MAK-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAK-001 ENSP00000313021
ENST00000313243
P20794
Show all »
Show » Show » 623 70.6 No 0
MAK-002 ENSP00000476067
ENST00000474039
Show » Show » 623 70.6 No 0
MAK-201 ENSP00000346484
ENST00000354489
P20794
Show all »
Show » Show » 623 70.6 No 0
MAK-202 ENSP00000442221
ENST00000536370
B3KUS6
Show all »
Show » Show » 288 33.6 No 0
MAK-203 ENSP00000442250
ENST00000538030
Q8IXN4
Show all »
Show » Show » 457 52.6 No 0