SLC26A8

GENERAL INFORMATION

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Gene name

SLC26A8

Gene description

Solute carrier family 26 (anion exchanger), member 8

Protein class

Disease related genes
Potential drug targets
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in testis. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 2 antibodies.
HPA038080 , HPA038081
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

SLC26A8

Synonyms

Description

Solute carrier family 26 (anion exchanger), member 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the SLC26 gene family of anion transporters. Family members are well conserved in gene structure and protein length yet have markedly different tissue expression patterns. The expression of this gene appears to be restricted to spermatocytes. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2010]

Chromosome

6

Cytoband

p21.31

Chromosome location (bp)

35943514 - 36024868

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112053 (version 78.38)

Entrez gene

116369

UniProt

Q96RN1 (UniProt - Evidence at protein level)

neXtProt

NX_Q96RN1

Antibodypedia

SLC26A8 antibodies


PROTEIN BROWSER

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ENST00000355574
 
ENST00000394602
 
ENST00000480663
 
ENST00000490799
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC26A8-001 ENSP00000417638
ENST00000490799
Q96RN1
Show all »
Show » Show » 970 109 No >9
SLC26A8-005 ENSP00000347778
ENST00000355574
Q96RN1
Show all »
Show » Show » 970 109 No >9
SLC26A8-006 ENSP00000378100
ENST00000394602
Q96RN1
Show all »
Show » Show » 865 97.4 No 8
SLC26A8-007 ENSP00000420488
ENST00000480663
C9JMV8
Show all »
Show » 190 21.4 No 0