ICK

GENE INFORMATION

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Gene name

ICK (HGNC Symbol)

Synonyms

KIAA0936, LCK2, MGC46090, MRK

Description

intestinal cell (MAK-like) kinase (HGNC Symbol)

Entrez gene summary

Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

p12.1

Chromosome location (bp)

52866077 - 52926600

Ensembl

ENSG00000112144 (version 73.37)

Entrez gene

22858

UniProt

Q9UPZ9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UPZ9

Antibodypedia

ICK antibodies
 

PROTEIN VIEW

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ICK-001
 
ICK-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ICK-001 ENSP00000263043
ENST00000350082
Q9UPZ9
Show all »
Show » Show » 632 71.4 No 0
ICK-201 ENSP00000349458
ENST00000356971
Q9UPZ9
Show all »
Show » Show » 632 71.4 No 0