BAG2

GENE INFORMATION

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Gene name

BAG2

Synonyms

Description

BCL2-associated athanogene 2 (HGNC Symbol)

Entrez gene summary

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

p11.2

Chromosome location (bp)

57037124 - 57054631

Ensembl

ENSG00000112208 (version 73.37)

Entrez gene

9532

UniProt

O95816 (UniProt - Evidence at protein level)

neXtProt

NX_O95816

Antibodypedia

BAG2 antibodies
 

PROTEIN VIEW

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BAG2-001
 
BAG2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BAG2-001 ENSP00000359727
ENST00000370693
O95816
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Show » 211 23.8 No 0
BAG2-201 ENSP00000441795
ENST00000545080
B4DXE2
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Show » 178 20.2 No 0