ASCC3

GENERAL INFORMATION

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Gene name

ASCC3

Gene description

Activating signal cointegrator 1 complex subunit 3

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA031608 , HPA031609 , HPA031610
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ASCC3 (HGNC Symbol)

Synonyms

ASC1p200, dJ121G13.4, dJ467N11.1, HELIC1, RNAH

Description

Activating signal cointegrator 1 complex subunit 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Chromosome

6

Cytoband

q16.3

Chromosome location (bp)

100508194 - 100881372

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112249 (version 78.38)

Entrez gene

10973

UniProt

Q8N3C0 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N3C0

Antibodypedia

ASCC3 antibodies


PROTEIN BROWSER

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ENST00000324723
 
ENST00000369143
 
ENST00000369162
 
ENST00000522650
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ASCC3-001 ENSP00000358159
ENST00000369162
Q8N3C0
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Show » Show » 2202 251.5 No 0
ASCC3-002 ENSP00000358139
ENST00000369143
Q8N3C0
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Show » Show » 111 13 No 0
ASCC3-004 ENSP00000430769
ENST00000522650
Q8N3C0
Show all »
Show » Show » 731 83.7 No 0
ASCC3-006 ENSP00000320777
ENST00000324723
E5RFZ0
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Show » Show » 176 19.8 No 0