SLC29A1

GENE INFORMATION

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Gene name

SLC29A1 (HGNC Symbol)

Synonyms

ENT1

Description

solute carrier family 29 (equilibrative nucleoside transporter), member 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

p21.1

Chromosome location (bp)

44187242 - 44201888

Ensembl

ENSG00000112759 (version 73.37)

Entrez gene

2030

UniProt

Q99808 (UniProt - Evidence at protein level)

neXtProt

NX_Q99808

Antibodypedia

SLC29A1 antibodies
 

PROTEIN VIEW

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SLC29A1-002
 
SLC29A1-003
 
SLC29A1-004
 
SLC29A1-005
 
SLC29A1-006
 
SLC29A1-007
 
SLC29A1-008
 
SLC29A1-201
 
SLC29A1-202
 
SLC29A1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC29A1-002 ENSP00000392668
ENST00000427851
Q99808
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Show » Show » 456 50.2 No >9
SLC29A1-003 ENSP00000360820
ENST00000371755
Q99808
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Show » Show » 456 50.2 No >9
SLC29A1-004 ENSP00000360805
ENST00000371740
Q99808
Show all »
Show » Show » 456 50.2 No >9
SLC29A1-005 ENSP00000360773
ENST00000371708
Q99808
Show all »
Show » Show » 456 50.2 No >9
SLC29A1-006 ENSP00000360796
ENST00000371731
Q99808
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Show » Show » 456 50.2 No >9
SLC29A1-007 ENSP00000360789
ENST00000371724
Q99808
Show all »
Show » Show » 456 50.2 No >9
SLC29A1-008 ENSP00000360778
ENST00000371713
Q99808
Show all »
Show » Show » 456 50.2 No >9
SLC29A1-201 ENSP00000319152
ENST00000313248
B3KQV7
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Show » Show » 535 59 No >9
SLC29A1-202 ENSP00000377424
ENST00000393841
Q99808
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Show » Show » 456 50.2 No >9
SLC29A1-203 ENSP00000377427
ENST00000393844
Q99808
Show all »
Show » Show » 456 50.2 No >9