SEMA5A

GENERAL INFORMATION

? »

Gene name

SEMA5A

Gene description

Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Intracellular,Membrane,Secreted

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Skeletal and smooth muscle, most squamous epithelia, urothelium and male genitalia showed moderate diffuse cytoplasmic positivity sometimes with small granules. Remaining normal cells were weakly stained or negative.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA004632
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

? »

Gene name

SEMA5A (HGNC Symbol)

Synonyms

SEMAF, semF

Description

Sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (HGNC Symbol)

Entrez gene summary

This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.[provided by RefSeq, Jan 2010]

Chromosome

5

Cytoband

p15.31

Chromosome location (bp)

9035026 - 9546075

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112902 (version 78.38)

Entrez gene

9037

UniProt

Q13591 (UniProt - Evidence at protein level)

neXtProt

NX_Q13591

Antibodypedia

SEMA5A antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000382496
 
ENST00000513968
 
ENST00000514923
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SEMA5A-001 ENSP00000371936
ENST00000382496
Q13591
Show all »
Show » Show » 1074 120.6 Yes 1
SEMA5A-002 ENSP00000421961
ENST00000513968
D6RAF4
Show all »
Show » Show » 254 28.6 Yes 0
SEMA5A-003 ENSP00000424171
ENST00000514923
Show » Show » 202 22.3 No 0