NNT

GENE INFORMATION

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Gene name

NNT

Synonyms

Description

nicotinamide nucleotide transhydrogenase (HGNC Symbol)

Entrez gene summary

This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

p12

Chromosome location (bp)

43602794 - 43707507

Ensembl

ENSG00000112992 (version 73.37)

Entrez gene

23530

UniProt

Q13423 (UniProt - Evidence at protein level)

neXtProt

NX_Q13423

Antibodypedia

NNT antibodies
 

PROTEIN VIEW

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NNT-001
 
NNT-002
 
NNT-004
 
NNT-006
 
NNT-007
 
NNT-008
 
NNT-010
 
NNT-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NNT-001 ENSP00000264663
ENST00000264663
Q13423
Show all »
Show » Show » 1086 113.9 No >9
NNT-002 ENSP00000343873
ENST00000344920
Q13423
Show all »
Show » Show » 1086 113.9 No >9
NNT-004 ENSP00000426343
ENST00000512996
E9PCX7
Show all »
Show » Show » 955 99.7 No >9
NNT-006 ENSP00000421886
ENST00000512422
D6RAI5
Show all »
Show » 217 23.5 No 0
NNT-007 ENSP00000425542
ENST00000515208
D6RCR6
Show all »
Show » 58 6.4 No 0
NNT-008 ENSP00000424782
ENST00000503059
11 1.2 No 0
NNT-010 ENSP00000421674
ENST00000503651
H0Y8P5
Show all »
57 6.1 No 0
NNT-012 ENSP00000427670
ENST00000505678
D6RHU2
Show all »
Show » 199 21.5 No 0