MRPS30

GENE INFORMATION

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Gene name

MRPS30 (HGNC Symbol)

Synonyms

PAP, PDCD9

Description

mitochondrial ribosomal protein S30 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52. Transcript variants using alternative promoters or polyA sites have been mentioned in the literature but the complete description of these sequences is not available. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

p12

Chromosome location (bp)

44809027 - 44820530

Ensembl

ENSG00000112996 (version 73.37)

Entrez gene

10884

UniProt

Q9NP92 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NP92

Antibodypedia

MRPS30 antibodies
 

PROTEIN VIEW

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MRPS30-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS30-001 ENSP00000424328
ENST00000507110
Q9NP92
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