GZMK

GENE INFORMATION

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Gene name

GZMK (HGNC Symbol)

Synonyms

PRSS, TRYP2

Description

granzyme K (granzyme 3; tryptase II) (HGNC Symbol)

Entrez gene summary

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

54320081 - 54330398

Ensembl

ENSG00000113088 (version 73.37)

Entrez gene

3003

UniProt

P49863 (UniProt - Evidence at protein level)

neXtProt

NX_P49863

Antibodypedia

GZMK antibodies
 

PROTEIN VIEW

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GZMK-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GZMK-001 ENSP00000231009
ENST00000231009
P49863
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