CLK4

GENE INFORMATION

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Gene name

CLK4

Synonyms

Description

CDC-like kinase 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q35.3

Chromosome location (bp)

178029665 - 178057616

Ensembl

ENSG00000113240 (version 73.37)

Entrez gene

57396

UniProt

Q9HAZ1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HAZ1

Antibodypedia

CLK4 antibodies
 

PROTEIN VIEW

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CLK4-001
 
CLK4-003
 
CLK4-004
 
CLK4-009
 
CLK4-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLK4-001 ENSP00000316948
ENST00000316308
Q9HAZ1
Show all »
Show » Show » 481 57.5 No 1
CLK4-003 ENSP00000428651
ENST00000521621
Q68D95
Show all »
Show » 53 6.6 No 0
CLK4-004 ENSP00000430216
ENST00000522556
E7EWJ6
Show all »
Show » 89 10.6 No 0
CLK4-009 ENSP00000429195
ENST00000522136
E7ES88
Show all »
Show » 143 17.7 No 0
CLK4-012 ENSP00000430892
ENST00000520957
Q6P090
Show all »
Show » 54 6.7 No 0