ITK

GENE INFORMATION

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Gene name

ITK (HGNC Symbol)

Synonyms

EMT, LYK, PSCTK2

Description

IL2-inducible T-cell kinase (HGNC Symbol)

Entrez gene summary

This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q33.3

Chromosome location (bp)

156569944 - 156682201

Ensembl

ENSG00000113263 (version 73.37)

Entrez gene

3702

UniProt

Q08881 (UniProt - Evidence at protein level)

neXtProt

NX_Q08881

Antibodypedia

ITK antibodies
 

PROTEIN VIEW

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ITK-001
 
ITK-007
 
ITK-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITK-001 ENSP00000398655
ENST00000422843
Q08881
Show all »
Show » Show » 620 71.8 No 0
ITK-007 ENSP00000431054
ENST00000517779
E5RJY4
Show all »
Show » Show » 116 13.8 No 0
ITK-008 ENSP00000430327
ENST00000521769
E5RFR5
Show all »
Show » Show » 73 8.5 No 0