FGF1

GENE INFORMATION

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Gene name

FGF1 (HGNC Symbol)

Synonyms

AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1

Description

fibroblast growth factor 1 (acidic) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]

Chromosome

5 (Chromosome progress)

Cytoband

q31.3

Chromosome location (bp)

141971743 - 142077617

Ensembl

ENSG00000113578 (version 73.37)

Entrez gene

2246

UniProt

P05230 (UniProt - Evidence at protein level)

neXtProt

NX_P05230

Antibodypedia

FGF1 antibodies
 

PROTEIN VIEW

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FGF1-001
 
FGF1-002
 
FGF1-004
 
FGF1-006
 
FGF1-007
 
FGF1-008
 
FGF1-009
 
FGF1-010
 
FGF1-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF1-001 ENSP00000352329
ENST00000359370
P05230
Show all »
Show » Show » 155 17.5 No 0
FGF1-002 ENSP00000338548
ENST00000337706
P05230
Show all »
Show » Show » 155 17.5 No 0
FGF1-004 ENSP00000378005
ENST00000394496
C9JDC5
Show all »
Show » 58 6.5 No 0
FGF1-006 ENSP00000404742
ENST00000441680
P05230
Show all »
Show » Show » 155 17.5 No 0
FGF1-007 ENSP00000354231
ENST00000360966
P05230
Show all »
Show » Show » 60 6.7 No 0
FGF1-008 ENSP00000367285
ENST00000378046
P05230
Show all »
Show » Show » 155 17.5 No 0
FGF1-009 ENSP00000383969
ENST00000407758
B5MCF4
Show all »
Show » 93 10.4 No 0
FGF1-010 ENSP00000396195
ENST00000419524
P05230
Show all »
Show » Show » 155 17.5 No 0
FGF1-013 ENSP00000399458
ENST00000411960
C9JUP6
Show all »
Show » 41 4.6 No 0