BCHE

GENE INFORMATION

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Gene name

BCHE (HGNC Symbol)

Synonyms

CHE1, CHE2, E1

Description

butyrylcholinesterase (HGNC Symbol)

Entrez gene summary

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q26.1

Chromosome location (bp)

165490692 - 165555260

Ensembl

ENSG00000114200 (version 73.37)

Entrez gene

590

UniProt

P06276 (UniProt - Evidence at protein level)

neXtProt

NX_P06276

Antibodypedia

BCHE antibodies
 

PROTEIN VIEW

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BCHE-001
 
BCHE-002
 
BCHE-003
 
BCHE-004
 
BCHE-005
 
BCHE-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BCHE-001 ENSP00000264381
ENST00000264381
P06276
Show all »
Show » Show » 602 68.4 Yes 0
BCHE-002 ENSP00000418325
ENST00000479451
H0Y885
Show all »
Show » 132 15.6 No 0
BCHE-003 ENSP00000419505
ENST00000497011
F8WF14
Show all »
Show » Show » 562 63.5 Yes 0
BCHE-004 ENSP00000419804
ENST00000482958
F8WEX7
Show all »
Show » Show » 525 58.9 Yes 0
BCHE-005 ENSP00000418504
ENST00000488954
H7C4Y0
Show all »
Show » 120 13.6 No 0
BCHE-201 ENSP00000443583
ENST00000540653
Q96HL2
Show all »
Show » 64 7.9 No 0