MRPL3

GENE INFORMATION

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Gene name

MRPL3 (HGNC Symbol)

Synonyms

MRL3, RPML3

Description

mitochondrial ribosomal protein L3 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

131181056 - 131221827

Ensembl

ENSG00000114686 (version 73.37)

Entrez gene

11222

UniProt

P09001 (UniProt - Evidence at protein level)

neXtProt

NX_P09001

Antibodypedia

MRPL3 antibodies
 

PROTEIN VIEW

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MRPL3-001
 
MRPL3-002
 
MRPL3-003
 
MRPL3-004
 
MRPL3-007
 
MRPL3-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL3-001 ENSP00000264995
ENST00000264995
P09001
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Show » Show » 348 38.6 No 0
MRPL3-002 ENSP00000424107
ENST00000511168
B4DW56
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Show » 363 40.5 No 0
MRPL3-003 ENSP00000398536
ENST00000425847
E7ETU7
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Show » Show » 375 41.6 No 0
MRPL3-004 ENSP00000422622
ENST00000510154
D6RBQ5
Show all »
Show » 28 3.3 No 0
MRPL3-007 ENSP00000422419
ENST00000507669
D6RC14
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Show » 155 17.1 No 0
MRPL3-010 ENSP00000422035
ENST00000512877
E9PF06
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Show » 176 19.6 No 0