ARHGEF26

GENE INFORMATION

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Gene name

ARHGEF26 (HGNC Symbol)

Synonyms

DKFZP434D146, SGEF

Description

Rho guanine nucleotide exchange factor (GEF) 26 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Chromosome

3

Cytoband

q25.2

Chromosome location (bp)

153838792 - 153975616

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000114790 (version 75.37)

Entrez gene

26084

UniProt

Q96DR7 (UniProt - Evidence at protein level)

neXtProt

NX_Q96DR7

Antibodypedia

ARHGEF26 antibodies
 

PROTEIN VIEW

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ARHGEF26-001
 
ARHGEF26-002
 
ARHGEF26-003
 
ARHGEF26-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGEF26-001 ENSP00000348828
ENST00000356448
Q96DR7
Show all »
Show » Show » 871 97.3 No 0
ARHGEF26-002 ENSP00000423418
ENST00000465093
Q96DR7
Show all »
Show » Show » 871 97.3 No 0
ARHGEF26-003 ENSP00000424446
ENST00000496710
Q96DR7
Show all »
Show » Show » 791 88.1 No 0
ARHGEF26-004 ENSP00000423295
ENST00000465817
Q96DR7
Show all »
Show » Show » 446 48.2 No 0