KCNIP3

GENE INFORMATION

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Gene name

KCNIP3 (HGNC Symbol)

Synonyms

calsenilin, CSEN, DREAM, KCHIP3

Description

Kv channel interacting protein 3, calsenilin (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q11.1

Chromosome location (bp)

95963052 - 96051825

Ensembl

ENSG00000115041 (version 73.37)

Entrez gene

30818

UniProt

Q9Y2W7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y2W7

Antibodypedia

KCNIP3 antibodies
 

PROTEIN VIEW

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KCNIP3-001
 
KCNIP3-004
 
KCNIP3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNIP3-001 ENSP00000295225
ENST00000295225
Q9Y2W7
Show all »
Show » 256 29.2 No 0
KCNIP3-004 ENSP00000417499
ENST00000468529
Q9Y2W7
Show all »
Show » Show » 230 26.3 Yes 0
KCNIP3-201 ENSP00000354261
ENST00000360990
Show » 234 26.8 No 0