PPM1G

GENE INFORMATION

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Gene name

PPM1G (HGNC Symbol)

Synonyms

PP2CG, PP2Cgamma

Description

protein phosphatase, Mg2+/Mn2+ dependent, 1G (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]

Chromosome

2 (Chromosome progress)

Cytoband

p23.3

Chromosome location (bp)

27604061 - 27632554

Ensembl

ENSG00000115241 (version 73.37)

Entrez gene

5496

UniProt

O15355 (UniProt - Evidence at protein level)

neXtProt

NX_O15355

Antibodypedia

PPM1G antibodies
 

PROTEIN VIEW

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PPM1G-001
 
PPM1G-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPM1G-001 ENSP00000342778
ENST00000344034
O15355
Show all »
Show » Show » 546 59.3 No 0
PPM1G-201 ENSP00000264714
ENST00000350803
O15355
Show all »
Show » Show » 546 59.3 No 0