GRB14

GENE INFORMATION

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Gene name

GRB14

Synonyms

Description

growth factor receptor-bound protein 14 (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q24.3

Chromosome location (bp)

165349322 - 165478358

Ensembl

ENSG00000115290 (version 73.37)

Entrez gene

2888

UniProt

Q14449 (UniProt - Evidence at protein level)

neXtProt

NX_Q14449

Antibodypedia

GRB14 antibodies
 

PROTEIN VIEW

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GRB14-001
 
GRB14-002
 
GRB14-005
 
GRB14-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRB14-001 ENSP00000263915
ENST00000263915
Q14449
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Show » Show » 540 61 No 0
GRB14-002 ENSP00000416786
ENST00000446413
C9JD37
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Show » 416 47.6 No 0
GRB14-005 ENSP00000401702
ENST00000424693
C9JLT6
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Show » 155 18.3 No 0
GRB14-201 ENSP00000443699
ENST00000543549
B7Z7F9
Show all »
Show » Show » 453 51.9 No 0