MRPL19

GENE INFORMATION

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Gene name

MRPL19 (HGNC Symbol)

Synonyms

KIAA0104, MRP-L15, RLX1, RPML15

Description

mitochondrial ribosomal protein L19 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p12

Chromosome location (bp)

75873909 - 75917977

Ensembl

ENSG00000115364 (version 73.37)

Entrez gene

9801

UniProt

P49406 (UniProt - Evidence at protein level)

neXtProt

NX_P49406

Antibodypedia

MRPL19 antibodies
 

PROTEIN VIEW

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MRPL19-001
 
MRPL19-002
 
MRPL19-004
 
MRPL19-005
 
MRPL19-006
 
MRPL19-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL19-001 ENSP00000377486
ENST00000393909
P49406
Show all »
Show » Show » 292 33.5 No 0
MRPL19-002 ENSP00000387284
ENST00000409374
P49406
Show all »
Show » Show » 292 33.5 No 0
MRPL19-004 ENSP00000474821
ENST00000476622
Show » 143 16.6 No 0
MRPL19-005 ENSP00000351639
ENST00000358788
H7BY27
Show all »
Show » 173 19.1 No 0
MRPL19-006 ENSP00000406267
ENST00000453233
H7C2J0
Show all »
Show » 79 9.7 No 0
MRPL19-007 ENSP00000475090
ENST00000492255
58 6.5 No 0