GGCX

GENE INFORMATION

? »

Gene name

GGCX (HGNC Symbol)

Synonyms

VKCFD1

Description

gamma-glutamyl carboxylase (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p11.2

Chromosome location (bp)

85774743 - 85788670

Ensembl

ENSG00000115486 (version 73.37)

Entrez gene

2677

UniProt

P38435 (UniProt - Evidence at protein level)

neXtProt

NX_P38435

Antibodypedia

GGCX antibodies
 

PROTEIN VIEW

? »
 
 
 
GGCX-001
 
GGCX-002
 
GGCX-005
 
GGCX-007
 
GGCX-009
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GGCX-001 ENSP00000233838
ENST00000233838
P38435
Show all »
Show » Show » 758 87.6 No 7
GGCX-002 ENSP00000389426
ENST00000423570
F8WDU9
Show all »
Show » Show » 123 13.7 No 1
GGCX-005 ENSP00000390748
ENST00000428479
F8WB98
Show all »
Show » Show » 73 8.2 No 1
GGCX-007 ENSP00000408045
ENST00000430215
P38435
Show all »
Show » Show » 701 81 No 6
GGCX-009 ENSP00000400384
ENST00000421496
F8WCF0
Show all »
Show » 66 7.2 No 0