EPAS1

GENE INFORMATION

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Gene name

EPAS1 (HGNC Symbol)

Synonyms

bHLHe73, HIF2A, HLF, MOP2, PASD2

Description

endothelial PAS domain protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]

Chromosome

2 (Chromosome progress)

Cytoband

p21

Chromosome location (bp)

46520806 - 46613836

Ensembl

ENSG00000116016 (version 73.37)

Entrez gene

2034

UniProt

Q99814 (UniProt - Evidence at protein level)

neXtProt

NX_Q99814

Antibodypedia

EPAS1 antibodies
 

PROTEIN VIEW

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EPAS1-001
 
EPAS1-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPAS1-001 ENSP00000263734
ENST00000263734
Q99814
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Show » Show » 870 96.5 No 0
EPAS1-007 ENSP00000406137
ENST00000449347
C9J9N2
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Show » Show » 259 29.6 No 0