ICMT

GENE INFORMATION

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Gene name

ICMT (HGNC Symbol)

Synonyms

HSTE14, PCCMT, PPMT

Description

isoprenylcysteine carboxyl methyltransferase (HGNC Symbol)

Entrez gene summary

This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p36.31

Chromosome location (bp)

6281253 - 6296032

Ensembl

ENSG00000116237 (version 73.37)

Entrez gene

23463

UniProt

O60725 (UniProt - Evidence at protein level)

neXtProt

NX_O60725

Antibodypedia

ICMT antibodies
 

PROTEIN VIEW

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ICMT-001
 
ICMT-002
 
ICMT-006
 
ICMT-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ICMT-001 ENSP00000343552
ENST00000343813
O60725
Show all »
Show » Show » 284 31.9 No 6
ICMT-002 ENSP00000466222
ENST00000489498
Q7Z750
Show all »
Show » Show » 116 12.5 No 2
ICMT-006 ENSP00000467999
ENST00000474756
K7EQW0
Show all »
Show » Show » 94 9.9 No 2
ICMT-201 ENSP00000354894
ENST00000362035
Q7Z750
Show all »
Show » Show » 116 12.5 No 2