PARK7

GENE INFORMATION

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Gene name

PARK7 (HGNC Symbol)

Synonyms

DJ-1, DJ1

Description

parkinson protein 7 (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p36.23

Chromosome location (bp)

8014351 - 8045565

Ensembl

ENSG00000116288 (version 73.37)

Entrez gene

11315

UniProt

Q99497 (UniProt - Evidence at protein level)

neXtProt

NX_Q99497

Antibodypedia

PARK7 antibodies
 

PROTEIN VIEW

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PARK7-001
 
PARK7-002
 
PARK7-003
 
PARK7-004
 
PARK7-005
 
PARK7-006
 
PARK7-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PARK7-001 ENSP00000418770
ENST00000493678
Q99497
Show all »
Show » Show » 189 19.9 No 0
PARK7-002 ENSP00000340278
ENST00000338639
Q99497
Show all »
Show » Show » 189 19.9 No 0
PARK7-003 ENSP00000466242
ENST00000377493
K7ELW0
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169 17.9 No 0
PARK7-004 ENSP00000465404
ENST00000493373
Q99497
Show all »
Show » Show » 189 19.9 No 0
PARK7-005 ENSP00000366711
ENST00000377491
Q99497
Show all »
Show » Show » 189 19.9 No 0
PARK7-006 ENSP00000366708
ENST00000377488
Q99497
Show all »
Show » Show » 189 19.9 No 0
PARK7-010 ENSP00000466756
ENST00000469225
K7EN27
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160 17 No 0