CD2

GENE INFORMATION

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Gene name

CD2 (HGNC Symbol)

Synonyms

SRBC

Description

CD2 molecule (HGNC Symbol)

Entrez gene summary

CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]

Chromosome

1 (Chromosome progress)

Cytoband

p13.1

Chromosome location (bp)

117297007 - 117311850

Ensembl

ENSG00000116824 (version 73.37)

Entrez gene

914

UniProt

P06729 (UniProt - Evidence at protein level)

neXtProt

NX_P06729

Antibodypedia

CD2 antibodies
 

PROTEIN VIEW

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CD2-001
 
CD2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD2-001 ENSP00000358490
ENST00000369478
P06729
Show all »
Show » Show » 351 39.4 Yes 1
CD2-002 ENSP00000358489
ENST00000369477
Q5JVN7
Show all »
Show » Show » 133 15.3 Yes 0