AKT3

GENE INFORMATION

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Gene name

AKT3 (HGNC Symbol)

Synonyms

PKBG, PRKBG, RAC-gamma

Description

v-akt murine thymoma viral oncogene homolog 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q43

Chromosome location (bp)

243651535 - 244014381

Ensembl

ENSG00000117020 (version 73.37)

Entrez gene

10000

UniProt

Q9Y243 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y243

Antibodypedia

AKT3 antibodies
 

PROTEIN VIEW

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AKT3-001
 
AKT3-002
 
AKT3-007
 
AKT3-008
 
AKT3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AKT3-001 ENSP00000355497
ENST00000366539
Q9Y243
Show all »
Show » Show » 479 55.8 No 0
AKT3-002 ENSP00000336943
ENST00000336199
Q9Y243
Show all »
Show » Show » 465 54 No 0
AKT3-007 ENSP00000355498
ENST00000366540
Q9Y243
Show all »
Show » Show » 465 54 No 0
AKT3-008 ENSP00000447820
ENST00000552631
F8VS91
Show all »
Show » 139 16.4 No 0
AKT3-201 ENSP00000263826
ENST00000263826
Q9Y243
Show all »
Show » Show » 479 55.8 No 0