ACADM

GENE INFORMATION

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Gene name

ACADM (HGNC Symbol)

Synonyms

ACAD1, MCAD, MCADH

Description

acyl-CoA dehydrogenase, C-4 to C-12 straight chain (HGNC Symbol)

Entrez gene summary

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p31.1

Chromosome location (bp)

76190036 - 76253260

Ensembl

ENSG00000117054 (version 73.37)

Entrez gene

34

UniProt

P11310 (UniProt - Evidence at protein level)

neXtProt

NX_P11310

Antibodypedia

ACADM antibodies
 

PROTEIN VIEW

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 « 
 
ACADM-001
 
ACADM-002
 
ACADM-005
 
ACADM-006
 
ACADM-007
 
ACADM-009
 
ACADM-010
 
ACADM-015
 
ACADM-016
 
ACADM-017
 
ACADM-201
 
ACADM-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACADM-001 ENSP00000359878
ENST00000370841
P11310
Show all »
Show » Show » 421 46.6 No 0
ACADM-002 ENSP00000359871
ENST00000370834
Q5T4U5
Show all »
Show » Show » 454 50.3 No 0
ACADM-005 ENSP00000409612
ENST00000420607
P11310
Show all »
Show » Show » 425 47 No 0
ACADM-006 ENSP00000431953
ENST00000526196
E9PIX8
Show all »
47 5.4 No 0
ACADM-007 ENSP00000434823
ENST00000525808
E9PIX8
Show all »
47 5.4 No 0
ACADM-009 ENSP00000434092
ENST00000526129
E9PRX4
Show all »
Show » 76 9 No 0
ACADM-010 ENSP00000435584
ENST00000534334
E9PJM9
Show all »
Show » 104 12.3 No 0
ACADM-015 ENSP00000432522
ENST00000532509
E9PQA8
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45 5.1 No 0
ACADM-016 ENSP00000431372
ENST00000530953
E9PLN7
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50 5.9 No 0
ACADM-017 ENSP00000434284
ENST00000528016
H0YDT5
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Show » 67 7.1 No 0
ACADM-201 ENSP00000442324
ENST00000541113
B7Z9I1
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Show » Show » 385 42.4 No 0
ACADM-202 ENSP00000446176
ENST00000543667
B4DJE7
Show all »
Show » Show » 232 25.7 No 0