LPHN2

GENE INFORMATION

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Gene name

LPHN2 (HGNC Symbol)

Synonyms

KIAA0786, LEC1, LPHH1

Description

latrophilin 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. While several transcript variants have been described, the biological validity of only one has been determined. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p31.1

Chromosome location (bp)

81771845 - 82458120

Ensembl

ENSG00000117114 (version 73.37)

Entrez gene

23266

UniProt

O95490 (UniProt - Evidence at protein level)

neXtProt

NX_O95490

Antibodypedia

LPHN2 antibodies
 

PROTEIN VIEW

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 « 
 
LPHN2-001
 
LPHN2-002
 
LPHN2-003
 
LPHN2-004
 
LPHN2-005
 
LPHN2-006
 
LPHN2-007
 
LPHN2-008
 
LPHN2-009
 
LPHN2-010
 
LPHN2-011
 
LPHN2-012
 
LPHN2-201
 
LPHN2-202
 
LPHN2-203
 
LPHN2-204
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LPHN2-001 ENSP00000353006
ENST00000359929
O95490
Show all »
Show » Show » 1403 157.2 Yes 7
LPHN2-002 ENSP00000359750
ENST00000370715
O95490
Show all »
Show » Show » 1177 132.2 Yes 7
LPHN2-003 ENSP00000359748
ENST00000370713
O95490
Show all »
Show » Show » 1123 126.2 Yes 7
LPHN2-004 ENSP00000322270
ENST00000319517
O95490
Show all »
Show » Show » 1403 157.2 Yes 7
LPHN2-005 ENSP00000359756
ENST00000370721
B1ALU1
Show all »
Show » Show » 1384 155.5 Yes 7
LPHN2-006 ENSP00000385853
ENST00000402328
Q9UJ49
Show all »
Show » Show » 471 52.3 No 2
LPHN2-007 ENSP00000359763
ENST00000370728
O95490
Show all »
Show » Show » 1459 163.3 Yes 7
LPHN2-008 ENSP00000359765
ENST00000370730
O95490
Show all »
Show » Show » 1416 158.8 Yes 7
LPHN2-009 ENSP00000359762
ENST00000370727
B1ALU3
Show all »
Show » Show » 1431 160.5 Yes 7
LPHN2-010 ENSP00000359760
ENST00000370725
O95490
Show all »
Show » Show » 1474 165.1 Yes 7
LPHN2-011 ENSP00000359758
ENST00000370723
O95490
Show all »
Show » Show » 1461 163.4 Yes 7
LPHN2-012 ENSP00000397740
ENST00000449420
Q9UJ49
Show all »
Show » Show » 1351 151.1 No 7
LPHN2-201 ENSP00000271029
ENST00000271029
B1ALU3
Show all »
Show » Show » 1431 160.5 Yes 7
LPHN2-202 ENSP00000337306
ENST00000335786
O95490
Show all »
Show » Show » 1416 158.8 Yes 7
LPHN2-203 ENSP00000359752
ENST00000370717
O95490
Show all »
Show » Show » 1474 165.1 Yes 7
LPHN2-204 ENSP00000378344
ENST00000394879
O95490
Show all »
Show » Show » 1461 163.4 Yes 7