DARS2

CANCER ATLAS

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Gene description

Aspartyl-tRNA synthetase 2, mitochondrial

Protein class

Disease related genes, Enzymes, Mitochondrial proteins, Potential drug targets, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA026506
 
HPA026528
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Moderate to strong often granular cytoplasmic immunoreactivity was observed in malignant tissues. Most skin, hepatocellular and renal cancers were weakly stained or negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected