PPP1R8

GENE INFORMATION

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Gene name

PPP1R8 (HGNC Symbol)

Synonyms

ard-1, ARD1, NIPP-1, NIPP1, PRO2047

Description

protein phosphatase 1, regulatory subunit 8 (HGNC Symbol)

Entrez gene summary

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p35.3

Chromosome location (bp)

28157289 - 28178187

Ensembl

ENSG00000117751 (version 73.37)

Entrez gene

5511

UniProt

Q12972 (UniProt - Evidence at protein level)

neXtProt

NX_Q12972

Antibodypedia

PPP1R8 antibodies
 

PROTEIN VIEW

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PPP1R8-001
 
PPP1R8-002
 
PPP1R8-003
 
PPP1R8-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPP1R8-001 ENSP00000311677
ENST00000311772
Q12972
Show all »
Show » 351 38.5 No 0
PPP1R8-002 ENSP00000363042
ENST00000373931
Q12972
Show all »
Show » 209 22.7 No 0
PPP1R8-003 ENSP00000236412
ENST00000236412
Q12972
Show all »
Show » 127 13.3 No 0
PPP1R8-005 ENSP00000410206
ENST00000431586
Q12972
Show all »
Show » 205 22.3 No 0