TNNT2

GENE INFORMATION

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Gene name

TNNT2 (HGNC Symbol)

Synonyms

CMH2

Description

troponin T type 2 (cardiac) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q32.1

Chromosome location (bp)

201328136 - 201346890

Ensembl

ENSG00000118194 (version 73.37)

Entrez gene

7139

UniProt

P45379 (UniProt - Evidence at protein level)

neXtProt

NX_P45379

Antibodypedia

TNNT2 antibodies
 

PROTEIN VIEW

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 « 
 
TNNT2-001
 
TNNT2-002
 
TNNT2-003
 
TNNT2-005
 
TNNT2-008
 
TNNT2-010
 
TNNT2-012
 
TNNT2-014
 
TNNT2-201
 
TNNT2-202
 
TNNT2-203
 
TNNT2-204
 
TNNT2-205
 
TNNT2-206
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TNNT2-001 ENSP00000356291
ENST00000367322
P45379
Show all »
Show » Show » 285 34.3 No 0
TNNT2-002 ENSP00000414036
ENST00000438742
E7EPW4
Show all »
Show » 271 32.7 No 0
TNNT2-003 ENSP00000356289
ENST00000367320
P45379
Show all »
Show » Show » 255 30.7 No 0
TNNT2-005 ENSP00000356287
ENST00000367318
P45379
Show all »
Show » Show » 288 34.6 No 0
TNNT2-008 ENSP00000422031
ENST00000509001
P45379
Show all »
Show » Show » 288 34.6 No 0
TNNT2-010 ENSP00000402238
ENST00000455702
E7EPN8
Show all »
Show » 180 21.8 No 0
TNNT2-012 ENSP00000408731
ENST00000412633
C9JM61
Show all »
98 11.4 No 0
TNNT2-014 ENSP00000395163
ENST00000422165
C9JDF8
Show all »
114 13.5 No 0
TNNT2-201 ENSP00000236918
ENST00000236918
F8W748
Show all »
Show » 293 35.4 No 0
TNNT2-202 ENSP00000353535
ENST00000360372
F8W9V2
Show all »
Show » 283 34 No 0
TNNT2-203 ENSP00000356284
ENST00000367315
P45379
Show all »
Show » Show » 285 34.3 No 0
TNNT2-204 ENSP00000356286
ENST00000367317
P45379
Show all »
Show » Show » 288 34.6 No 0
TNNT2-205 ENSP00000404134
ENST00000421663
J3KQN2
Show all »
Show » 291 35 No 0
TNNT2-206 ENSP00000387874
ENST00000458432
F8WAF6
Show all »
Show » 297 35.8 No 0