CNR1

GENE INFORMATION

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Gene name

CNR1 (HGNC Symbol)

Synonyms

CANN6, CB-R, CB1, CB1A, CB1K5, CNR

Description

cannabinoid receptor 1 (brain) (HGNC Symbol)

Entrez gene summary

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]

Chromosome

6 (Chromosome progress)

Cytoband

q15

Chromosome location (bp)

88849583 - 88876078

Ensembl

ENSG00000118432 (version 73.37)

Entrez gene

1268

UniProt

P21554 (UniProt - Evidence at protein level)

neXtProt

NX_P21554

Antibodypedia

CNR1 antibodies
 

PROTEIN VIEW

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CNR1-001
 
CNR1-002
 
CNR1-003
 
CNR1-004
 
CNR1-005
 
CNR1-006
 
CNR1-007
 
CNR1-201
 
CNR1-202
 
CNR1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CNR1-001 ENSP00000358513
ENST00000369501
P21554
Show all »
Show » Show » 472 52.9 No 7
CNR1-002 ENSP00000446819
ENST00000549890
P21554
Show all »
Show » Show » 472 52.9 No 7
CNR1-003 ENSP00000355418
ENST00000362094
F8W908
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36 4 No 0
CNR1-004 ENSP00000420188
ENST00000468898
P21554
Show all »
Show » Show » 439 49.1 No 7
CNR1-005 ENSP00000412192
ENST00000428600
P21554
Show all »
Show » Show » 472 52.9 No 7
CNR1-006 ENSP00000358511
ENST00000369499
P21554
Show all »
Show » Show » 472 52.9 No 7
CNR1-007 ENSP00000446702
ENST00000551417
F8W187
Show all »
Show » 78 8.7 No 0
CNR1-201 ENSP00000442689
ENST00000535130
P21554
Show all »
Show » Show » 472 52.9 No 7
CNR1-202 ENSP00000441046
ENST00000537554
P21554
Show all »
Show » Show » 472 52.9 No 7
CNR1-203 ENSP00000449549
ENST00000549716
P21554
Show all »
Show » Show » 411 45.9 No 7