MYL12B

GENE INFORMATION

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Gene name

MYL12B (HGNC Symbol)

Synonyms

MRLC2

Description

myosin, light chain 12B, regulatory (HGNC Symbol)

Entrez gene summary

The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM, Mar 2008]

Chromosome

18 (Chromosome progress)

Cytoband

p11.31

Chromosome location (bp)

3261907 - 3278282

Ensembl

ENSG00000118680 (version 73.37)

Entrez gene

103910

UniProt

O14950 (UniProt - Evidence at protein level)

neXtProt

NX_O14950

Antibodypedia

MYL12B antibodies
 

PROTEIN VIEW

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MYL12B-001
 
MYL12B-002
 
MYL12B-003
 
MYL12B-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MYL12B-001 ENSP00000237500
ENST00000237500
O14950
Show all »
Show » 172 19.8 No 0
MYL12B-002 ENSP00000463559
ENST00000581193
O14950
Show all »
Show » 172 19.8 No 0
MYL12B-003 ENSP00000383037
ENST00000400175
O14950
Show all »
Show » 172 19.8 No 0
MYL12B-004 ENSP00000464464
ENST00000584539
O14950
Show all »
Show » 172 19.8 No 0