SENP5

GENE INFORMATION

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Gene name

SENP5 (HGNC Symbol)

Synonyms

MGC27076

Description

SUMO1/sentrin specific peptidase 5 (HGNC Symbol)

Entrez gene summary

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]

Chromosome

3 (Chromosome progress)

Cytoband

q29

Chromosome location (bp)

196594727 - 196661585

Ensembl

ENSG00000119231 (version 73.37)

Entrez gene

205564

UniProt

Q96HI0 (UniProt - Evidence at protein level)

neXtProt

NX_Q96HI0

Antibodypedia

SENP5 antibodies
 

PROTEIN VIEW

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SENP5-001
 
SENP5-002
 
SENP5-003
 
SENP5-005
 
SENP5-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SENP5-001 ENSP00000327197
ENST00000323460
Q96HI0
Show all »
Show » Show » 755 86.7 No 0
SENP5-002 ENSP00000390231
ENST00000445299
B4DY82
Show all »
Show » 709 81.3 No 0
SENP5-003 ENSP00000396927
ENST00000419026
C9JHT8
Show all »
Show » 245 29.3 No 0
SENP5-005 ENSP00000405663
ENST00000448068
Show » 98 11.5 No 0
SENP5-006 ENSP00000415227
ENST00000434433
Show » 77 9.1 No 0