The cancer tissue page shows antibody staining in 20 different cancers. The overall cancer tissue staining statistics shows the fraction of patient samples with strong, moderate, weak or no staining (as described by the color-coding scale in the box to the right), using all the available antibodies to the protein targets encoded by this gene. The assay and annotation is described here.
The cancers can be ordered histologically or alphabetically.
For each cancer, the staining for each available antibody is reported as the fraction of samples with strong, moderate, weak or no staining (as described by the color-coding scale in the box to the right). The lenght of the bar represents the number of patient samples analysed (max=12 patients). By clicking on a cancer tissue, the detailed staining data for that cancer is available, including annotated images.
At the bottom of this page, a summary for the cancer staining for each antibody is given, together with the immunohistochemistry validation score for that antibody.
Moderate to strong cytoplasmic positivity with a granular pattern was observed in most malignant cells. Several malignant lymphomas and several cases of squamous cell carcinomas were weakly stained or negative.
Most malignant cells displayed moderate to strong cytoplasmic positivity with a granular pattern. Most cases of malignant lymphomas, squamous cell carcinomas, urothelial, testicular, colorectal and gastric cancers were weakly stained or negative.
Most malignant cells showed moderate to strong cytoplasmic positivity with a granular pattern. Many cases of malignant carcinoids, malignant lymphomas, squamous cell carcinomas, testicular, urothelial and gastric cancers were weakly stained or negative.
A majority of malignant cells showed moderate to strong cytoplasmic positivity with a granular pattern. Most cases of malignant carcinoids and lymphomas as well as stomach and testis cancers were weakly stained or negative.
Validation
Two (or more) antibodies yielding similar staining patterns which are consistent with available gene/protein characterization data
Two (or more) antibodies yielding similar staining patterns which are consistent with available gene/protein characterization data
Two (or more) antibodies yielding similar staining patterns which are consistent with available gene/protein characterization data
Two (or more) antibodies yielding similar staining patterns which are consistent with available gene/protein characterization data
