FKBP1B

GENE INFORMATION

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Gene name

FKBP1B (HGNC Symbol)

Synonyms

FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase

Description

FK506 binding protein 1B, 12.6 kDa (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p23.3

Chromosome location (bp)

24272571 - 24286551

Ensembl

ENSG00000119782 (version 73.37)

Entrez gene

2281

UniProt

P68106 (UniProt - Evidence at protein level)

neXtProt

NX_P68106

Antibodypedia

FKBP1B antibodies
 

PROTEIN VIEW

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FKBP1B-001
 
FKBP1B-002
 
FKBP1B-003
 
FKBP1B-004
 
FKBP1B-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FKBP1B-001 ENSP00000370373
ENST00000380986
P68106
Show all »
Show » Show » 108 11.8 No 0
FKBP1B-002 ENSP00000370379
ENST00000380991
P68106
Show all »
Show » Show » 80 8.8 No 0
FKBP1B-003 ENSP00000416349
ENST00000438630
G5E9U6
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57 6.1 No 0
FKBP1B-004 ENSP00000397444
ENST00000421839
42 4.4 No 0
FKBP1B-006 ENSP00000406593
ENST00000452109
F8W6G9
Show all »
Show » 79 8.7 No 0