WDR11

GENE INFORMATION

? »

Gene name

WDR11 (HGNC Symbol)

Synonyms

BRWD2, DR11, FLJ10506, HH14, KIAA1351, WDR15

Description

WD repeat domain 11 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q26.12

Chromosome location (bp)

122610687 - 122669036

Ensembl

ENSG00000120008 (version 73.37)

Entrez gene

55717

UniProt

Q9BZH6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BZH6

Antibodypedia

WDR11 antibodies
 

PROTEIN VIEW

? »
 
 
 
WDR11-001
 
WDR11-002
 
WDR11-007
 
WDR11-016
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WDR11-001 ENSP00000263461
ENST00000263461
Q9BZH6
Show all »
Show » Show » 1224 136.7 No 1
WDR11-002 ENSP00000474595
ENST00000497136
199 22.4 No 0
WDR11-007 ENSP00000475076
ENST00000605543
Show » 95 10.3 No 0
WDR11-016 ENSP00000474880
ENST00000604585
Show » 312 34.3 No 0