MRPS14

GENE INFORMATION

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Gene name

MRPS14 (HGNC Symbol)

Synonyms

HSMRPS14

Description

mitochondrial ribosomal protein S14 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Chromosome

1 (Chromosome progress)

Cytoband

q25.1

Chromosome location (bp)

174979925 - 174992561

Ensembl

ENSG00000120333 (version 73.37)

Entrez gene

63931

UniProt

O60783 (UniProt - Evidence at protein level)

neXtProt

NX_O60783

Antibodypedia

MRPS14 antibodies
 

PROTEIN VIEW

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MRPS14-001
 
MRPS14-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS14-001 ENSP00000420714
ENST00000476371
O60783
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Show » Show » 128 15.1 Yes 0
MRPS14-002 ENSP00000431220
ENST00000367677
F2Z361
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60 6.7 Yes 0