Fields »

SUBCELLULAR LOCATION

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Main location(s)

Cytoplasm, Aggresome

Additional location(s)

 

Staining summary

Localized to aggresomes.

Reliability (APE)

Low

Antibodies in assay

HPA014014, HPA027108
 

Antibody HPA014014

 

Antibody HPA027108

 

         Cell line A-431

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Location(s)

   

Staining characteristics

   

Staining intensity

  Negative 

Validation

  
No staining.
 

Comment

   

         Cell line U-2 OS

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Location(s)

  Cytoplasm, Aggresome 

Staining characteristics

   

Staining intensity

  Weak 

Validation

  
Not decisive - One/multiple location(s) where experimental gene/protein characterization data is partly supporting and partly conflicting.
 

Comment

   

         Cell line U-251 MG

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Location(s)

  

Staining characteristics

  

Staining intensity

Negative Negative 

Validation

No staining.
 
No staining.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-251MG shows no positivity.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in cytoplasm & aggresome.
 

Summary

No specific staining was observed in the three cell lines.   Staining of cytoplasm and aggresome in U-2 OS.  

Validation

The subcellular location is not consistent with literature.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cell overview
Cytoplasm