TAF12

GENE INFORMATION

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Gene name

TAF12 (HGNC Symbol)

Synonyms

TAF2J, TAFII20

Description

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa (HGNC Symbol)

Entrez gene summary

Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p35.3

Chromosome location (bp)

28915835 - 28969597

Ensembl

ENSG00000120656 (version 73.37)

Entrez gene

6883

UniProt

Q16514 (UniProt - Evidence at protein level)

neXtProt

NX_Q16514

Antibodypedia

TAF12 antibodies
 

PROTEIN VIEW

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TAF12-001
 
TAF12-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TAF12-001 ENSP00000263974
ENST00000263974
Q16514
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Show » 161 17.9 No 0
TAF12-002 ENSP00000362930
ENST00000373824
Q16514
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Show » 161 17.9 No 0