TGFBI

GENE INFORMATION

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Gene name

TGFBI (HGNC Symbol)

Synonyms

BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1

Description

transforming growth factor, beta-induced, 68kDa (HGNC Symbol)

Entrez gene summary

This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q31.1

Chromosome location (bp)

135364584 - 135399507

Ensembl

ENSG00000120708 (version 73.37)

Entrez gene

7045

UniProt

Q15582 (UniProt - Evidence at protein level)

neXtProt

NX_Q15582

Antibodypedia

TGFBI antibodies
 

PROTEIN VIEW

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TGFBI-001
 
TGFBI-003
 
TGFBI-005
 
TGFBI-008
 
TGFBI-012
 
TGFBI-013
 
TGFBI-016
 
TGFBI-017
 
TGFBI-019
 
TGFBI-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TGFBI-001 ENSP00000416330
ENST00000442011
Q15582
Show all »
Show » Show » 683 74.7 Yes 0
TGFBI-003 ENSP00000421540
ENST00000507018
Show » 128 14.2 No 0
TGFBI-005 ENSP00000426137
ENST00000504205
D6RHG5
Show all »
Show » 63 6.9 Yes 0
TGFBI-008 ENSP00000421440
ENST00000514554
C7FFS5
Show all »
366 39.8 No 0
TGFBI-012 ENSP00000423871
ENST00000508767
194 21.1 No 0
TGFBI-013 ENSP00000426589
ENST00000509485
59 6.2 No 0
TGFBI-016 ENSP00000423935
ENST00000508076
D6RBX4
Show all »
Show » 65 7.3 No 0
TGFBI-017 ENSP00000427137
ENST00000503087
78 8.4 No 0
TGFBI-019 ENSP00000474155
ENST00000604555
219 23.5 No 0
TGFBI-201 ENSP00000306306
ENST00000305126
G8JLA8
Show all »
Show » Show » 683 74.7 Yes 0