ADRA1A

GENE INFORMATION

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Gene name

ADRA1A (HGNC Symbol)

Synonyms

ADRA1C, ADRA1L1

Description

adrenoceptor alpha 1A (HGNC Symbol)

Entrez gene summary

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]

Chromosome

8 (Chromosome progress)

Cytoband

p21.2

Chromosome location (bp)

26605667 - 26724790

Ensembl

ENSG00000120907 (version 73.37)

Entrez gene

148

UniProt

P35348 (UniProt - Evidence at protein level)

neXtProt

NX_P35348

Antibodypedia

ADRA1A antibodies
 

PROTEIN VIEW

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 « 
 
ADRA1A-001
 
ADRA1A-002
 
ADRA1A-003
 
ADRA1A-004
 
ADRA1A-005
 
ADRA1A-006
 
ADRA1A-007
 
ADRA1A-008
 
ADRA1A-009
 
ADRA1A-201
 
ADRA1A-202
 
ADRA1A-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADRA1A-001 ENSP00000369956
ENST00000380582
P35348
Show all »
Show » Show » 429 47.5 No 7
ADRA1A-002 ENSP00000346557
ENST00000354550
P35348
Show all »
Show » Show » 455 50.8 No 7
ADRA1A-003 ENSP00000276393
ENST00000276393
P35348
Show all »
Show » Show » 466 51.5 No 7
ADRA1A-004 ENSP00000369960
ENST00000380586
P35348
Show all »
Show » Show » 475 52.2 No 7
ADRA1A-005 ENSP00000369946
ENST00000380572
P35348
Show all »
Show » Show » 342 37.5 No 6
ADRA1A-006 ENSP00000430414
ENST00000521711
P35348
Show all »
Show » Show » 324 35.8 No 6
ADRA1A-007 ENSP00000431073
ENST00000519096
P35348
Show all »
Show » Show » 324 35.8 No 6
ADRA1A-008 ENSP00000369947
ENST00000380573
P35348
Show all »
Show » Show » 466 51.5 No 7
ADRA1A-009 ENSP00000430793
ENST00000519229
E7EW16
Show all »
Show » Show » 427 47.2 No 7
ADRA1A-201 ENSP00000351725
ENST00000358857
P35348
Show all »
Show » Show » 324 35.8 No 6
ADRA1A-202 ENSP00000369955
ENST00000380581
P35348
Show all »
Show » Show » 372 40.6 No 6
ADRA1A-203 ENSP00000369961
ENST00000380587
P35348
Show all »
Show » Show » 370 40.7 No 6