RNF2

GENE INFORMATION

? »

Gene name

RNF2 (HGNC Symbol)

Synonyms

BAP-1, BAP1, DING, HIPI3, RING1B, RING2

Description

ring finger protein 2 (HGNC Symbol)

Entrez gene summary

Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

185014496 - 185071740

Ensembl

ENSG00000121481 (version 73.37)

Entrez gene

6045

UniProt

Q99496 (UniProt - Evidence at protein level)

neXtProt

NX_Q99496

Antibodypedia

RNF2 antibodies
 

PROTEIN VIEW

? »
 
 
 
RNF2-001
 
RNF2-002
 
RNF2-003
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RNF2-001 ENSP00000356480
ENST00000367510
Q99496
Show all »
Show » 336 37.7 No 0
RNF2-002 ENSP00000356479
ENST00000367509
B3KRH1
Show all »
Show » 264 29.3 No 0
RNF2-003 ENSP00000400722
ENST00000453650
Q99496
Show all »
Show » 246 27.4 No 0