CAT

GENE INFORMATION

? »

Gene name

CAT

Synonyms

Description

catalase (HGNC Symbol)

Entrez gene summary

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]

Chromosome

11 (Chromosome progress)

Cytoband

p13

Chromosome location (bp)

34460472 - 34493609

Ensembl

ENSG00000121691 (version 73.37)

Entrez gene

847

UniProt

P04040 (UniProt - Evidence at protein level)

neXtProt

NX_P04040

Antibodypedia

CAT antibodies
 

PROTEIN VIEW

? »
 
 
 
CAT-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CAT-001 ENSP00000241052
ENST00000241052
P04040
Show all »
Show » Show » 527 59.8 No 0