ACKR5

GENE INFORMATION

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Gene name

ACKR5 (HGNC Symbol)

Synonyms

CCRL2, CKRX, CRAM-A, CRAM-B, HCR

Description

atypical chemokine receptor 5 (HGNC Symbol)

Entrez gene summary

This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

p21.31

Chromosome location (bp)

46448654 - 46454488

Ensembl

ENSG00000121797 (version 73.37)

Entrez gene

9034

UniProt

O00421 (UniProt - Evidence at protein level)

neXtProt

NX_O00421

Antibodypedia

ACKR5 antibodies
 

PROTEIN VIEW

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ACKR5-001
 
ACKR5-002
 
ACKR5-003
 
ACKR5-004
 
ACKR5-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACKR5-001 ENSP00000349967
ENST00000357392
O00421
Show all »
Show » Show » 356 41 No 7
ACKR5-002 ENSP00000381994
ENST00000399036
O00421
Show all »
Show » Show » 344 39.5 No 7
ACKR5-003 ENSP00000383678
ENST00000400882
O00421
Show all »
Show » Show » 344 39.5 No 7
ACKR5-004 ENSP00000383677
ENST00000400880
O00421
Show all »
Show » Show » 344 39.5 No 7
ACKR5-005 ENSP00000414957
ENST00000433848
C9JP23
Show all »
Show » Show » 217 24.6 No 5