PIK3CA

GENE INFORMATION

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Gene name

PIK3CA (HGNC Symbol)

Synonyms

PI3K

Description

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (HGNC Symbol)

Entrez gene summary

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q26.32

Chromosome location (bp)

178865902 - 178957881

Ensembl

ENSG00000121879 (version 73.37)

Entrez gene

5290

UniProt

P42336 (UniProt - Evidence at protein level)

neXtProt

NX_P42336

Antibodypedia

PIK3CA antibodies
 

PROTEIN VIEW

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PIK3CA-001
 
PIK3CA-002
 
PIK3CA-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PIK3CA-001 ENSP00000263967
ENST00000263967
P42336
Show all »
Show » Show » 1068 124.3 No 0
PIK3CA-002 ENSP00000418145
ENST00000477735
C9J951
Show all »
Show » Show » 21 2.4 No 0
PIK3CA-003 ENSP00000417479
ENST00000468036
C9JAM9
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Show » Show » 118 13.8 No 0